Rheum undulatum L. - PMC

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Select item 60996081.

In Vitro Estrogenic and Breast Cancer Inhibitory Activities of Chemical Constituents Isolated from Rheum undulatum L.

Dahae Lee, SeonJu Park, Sungyoul Choi, Seung Hyun Kim, Ki Sung Kang

Molecules. 2018 May; 23(5): 1215. Published online 2018 May 18. doi: 10.3390/molecules23051215

PMCID:: PMC6099608

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Stilbenes contribute to the anticancer effects of Rheum undulatum L. through activation of apoptosis

Tuy An Trinh, Dahae Lee, Seonju Park, Seung Hyun Kim, Jae Gyu Park, Ji Hwan Kim, Ki Sung Kang

Oncol Lett. 2019 Mar; 17(3): 2953–2959. Published online 2019 Jan 14. doi: 10.3892/ol.2019.9926

PMCID:: PMC6365963

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Select item 71753773.

Network Pharmacology-Based Approaches of Rheum undulatum Linne and Glycyrriza uralensis Fischer Imply Their Regulation of Liver Failure with Hepatic Encephalopathy in Mice

Su Youn Baek, Eun Hye Lee, Tae Woo Oh, Hyun Ju Do, Kwang-Youn Kim, Kwang-Il Park, Young Woo Kim

Biomolecules. 2020 Mar; 10(3): 437. Published online 2020 Mar 12. doi: 10.3390/biom10030437

PMCID:: PMC7175377

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Emodin in Rheum undulatum inhibits oxidative stress in the liver via AMPK with Hippo/Yap signalling pathway

Eun Hye Lee, Su Youn Baek, Ji Young Park, Young Woo Kim

Pharm Biol. 2020; 58(1): 333–341. Published online 2020 Apr 20. doi: 10.1080/13880209.2020.1750658

PMCID:: PMC7191907

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Association of a Methanol Extract of Rheum undulatum L. Mediated Cell Death in AGS Cells with an Intrinsic Apoptotic Pathway

Noo Ri Hong, Hyun Soo Park, Tae Seok Ahn, Myeong Ho Jung, Byung Joo Kim

J Pharmacopuncture. 2015 Jun; 18(2): 26–32. doi: 10.3831/KPI.2015.18.012

PMCID:: PMC4481396

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The Apoptotic Effect of the Hexane Extract of Rheum undulatum L. in Oral Cancer Cells through the Down-regulation of Specificity Protein 1 and Survivin

Eun-Sun Choi, Sung-Dae Cho, Jae-Gyu Jeon, Nam-Pyo Cho

Lab Anim Res. 2011 Mar; 27(1): 19–24. Published online 2011 Mar 25. doi: 10.5625/lar.2011.27.1.19

PMCID:: PMC3145981

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Deoxyrhapontigenin, a Natural Stilbene Derivative Isolated From Rheum undulatum L. Induces Endoplasmic Reticulum Stress–Mediated Apoptosis in Human Breast Cancer Cells

Thamizhiniyan Venkatesan, Min-Ji Jeong, Young-Woong Choi, Eun-Jin Park, Samy Korany El-Desouky, Young-Kyoon Kim

Integr Cancer Ther. 2016 Dec; 15(4): NP44–NP52. Published online 2016 May 4. doi: 10.1177/1534735416636958

PMCID:: PMC5739162

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Rhaponticin decreases the metastatic and angiogenic abilities of cancer cells via suppression of the HIF-1α pathway

Aeyung Kim, Jin Yeul Ma

Int J Oncol. 2018 Sep; 53(3): 1160–1170. Published online 2018 Jul 11. doi: 10.3892/ijo.2018.4479

PMCID:: PMC6065401

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Characterization and Comparative Analysis of Two Rheum Complete Chloroplast Genomes

Kaihui Zhao, Lianqiang Li, Yazhou Lu, Junbo Yang, Zhirong Zhang, Fangyu Zhao, Hong Quan, Xiaojing Ma, Zhihua Liao, Xiaozhong Lan

Biomed Res Int. 2020; 2020: 6490164. Published online 2020 Jun 19. doi: 10.1155/2020/6490164

PMCID:: PMC7327605

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Desoxyrhapontigenin up-regulates Nrf2-mediated heme oxygenase-1 expression in macrophages and inflammatory lung injury

Ran Joo Choi, Mao-sheng Cheng, Yeong Shik Kim

Redox Biol. 2014; 2: 504–512. Published online 2014 Feb 18. doi: 10.1016/j.redox.2014.02.001

PMCID:: PMC3949088

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Comparison of the Phytochemical Properties, Antioxidant Activity and Cytotoxic Effect on HepG2 Cells in Mongolian and Taiwanese Rhubarb Species

Ganbolor Jargalsaikhan, Jin-Yi Wu, Yen-Chou Chen, Ling-Ling Yang, Ming-Shun Wu

Molecules. 2021 Mar; 26(5): 1217. Published online 2021 Feb 25. doi: 10.3390/molecules26051217

PMCID:: PMC7956657

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A Review on Rhubarb-Derived Substances as Modulators of Cardiovascular Risk Factors—A Special Emphasis on Anti-Obesity Action

Oleksandra Liudvytska, Joanna Kolodziejczyk-Czepas

Nutrients. 2022 May; 14(10): 2053. Published online 2022 May 13. doi: 10.3390/nu14102053

PMCID:: PMC9144273

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Select item 728462913.

Micropropagation, Genetic Fidelity and Phenolic Compound Production of Rheum rhabarbarum L.

Doina Clapa, Orsolya Borsai, Monica Hârța, Victoriţa Bonta, Katalin Szabo, Vasile Coman, Otilia Bobiș

Plants (Basel) 2020 May; 9(5): 656. Published online 2020 May 22. doi: 10.3390/plants9050656

PMCID:: PMC7284629

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Select item 424678314.

Molecular Phylogeny, Recent Radiation and Evolution of Gross Morphology of the Rhubarb genus Rheum (Polygonaceae) Inferred from Chloroplast DNA trnL-F Sequences

AILAN WANG, MEIHUA YANG, JIANQUAN LIU

Ann Bot. 2005 Sep; 96(3): 489–498. Published online 2005 Jul 1. doi: 10.1093/aob/mci201

PMCID:: PMC4246783

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Select item 860153815.

Ecological assessment and environmental niche modelling of Himalayan rhubarb (Rheum webbianum Royle) in northwest Himalaya

Ishfaq Ahmad Wani, Susheel Verma, Priyanka Kumari, Bipin Charles, Maha J. Hashim, Hamed A. El-Serehy

PLoS One. 2021; 16(11): e0259345. Published online 2021 Nov 18. doi: 10.1371/journal.pone.0259345

Correction in:: PLoS One. 2021; 16(12): e0261100.

PMCID:: PMC8601538

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Rheum rhaponticum and Rheum rhabarbarum Extracts as Modulators of Endothelial Cell Inflammatory Response

Oleksandra Liudvytska, Michał B. Ponczek, Oskar Ciesielski, Justyna Krzyżanowska-Kowalczyk, Mariusz Kowalczyk, Aneta Balcerczyk, Joanna Kolodziejczyk-Czepas

Nutrients. 2023 Feb; 15(4): 949. Published online 2023 Feb 14. doi: 10.3390/nu15040949

PMCID:: PMC9964395

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Select item 601345917.

Genetic and chemical differentiation characterizes top-geoherb and non-top-geoherb areas in the TCM herb rhubarb

Xumei Wang, Li Feng, Tao Zhou, Markus Ruhsam, Lei Huang, Xiaoqi Hou, Xiaojie Sun, Kai Fan, Min Huang, Yun Zhou, Jie Song

Sci Rep. 2018; 8: 9424. Published online 2018 Jun 21. doi: 10.1038/s41598-018-27510-1

PMCID:: PMC6013459

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Select item 489019218.

Development of an efficient callus proliferation system for Rheum coreanum Nakai, a rare medicinal plant growing in Democratic People’s Republic of Korea

Song-Chol Mun, Gwan-Sim Mun

Saudi J Biol Sci. 2016 Jul; 23(4): 488–494. Published online 2015 Jun 6. doi: 10.1016/j.sjbs.2015.05.017

PMCID:: PMC4890192

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Select item 620875219.

Investigation of species and environmental effects on rhubarb roots metabolome using ¹H NMR combined with high performance thin layer chromatography

Yanhui Ge, Mengmeng Sun, Luis F. Salomé-Abarca, Mei Wang, Young Hae Choi

Metabolomics. 2018; 14(10): 137. Published online 2018 Oct 4. doi: 10.1007/s11306-018-1421-1

PMCID:: PMC6208752

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Select item 700963320.

Safety of hydroxyanthracene derivatives for use in food

EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS), Maged Younes, Peter Aggett, Fernando Aguilar, Riccardo Crebelli, Metka Filipič, Maria Jose Frutos, Pierre Galtier, David Gott, Ursula Gundert‐Remy, Gunter Georg Kuhnle, Claude Lambré, Jean‐Charles Leblanc, Inger Therese Lillegaard, Peter Moldeus, Alicja Mortensen, Agneta Oskarsson, Ivan Stankovic, Ine Waalkens‐Berendsen, Rudolf Antonius Woutersen, Raul J Andrade, Cristina Fortes, Pasquale Mosesso, Patrizia Restani, Fabiola Pizzo, Camilla Smeraldi, Adamantia Papaioannou, Matthew Wright

EFSA J. 2018 Jan; 16(1): e05090. Published online 2018 Jan 23. doi: 10.2903/j.efsa.2018.5090

PMCID:: PMC7009633

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PMC Images search for Rheum undulatum L.

Figure 1

Comparison of the estrogenic activities of Rheum undulatum extracts (EX1, EX2, and EX3). (A) Comparison of the estrogenic effects of R. undulatum extracts on MCF-7 cell proliferation measured by E-screen assay. (B) Comparison of the estrogenic effects of R. undulatum extracts in the absence or presence of fulvestrant on MCF-7 cell proliferation measured by E-screen assay; * p < 0.05 compared to the control value.

In Vitro Estrogenic and Breast Cancer Inhibitory Activities of Chemical Constituents Isolated from Rheum undulatum L.

Molecules. 2018 May;23(5):1215.
Figure 3

The effect of hexane extract of Rheum undulatum L. (HERL) on the condensation and fragmentation of nucleus in HN22 and SCC15 cells. Fluorescence microscopy images of DAPI-stained HN22 and SCC15 cells showing the appearance of apoptotic morphology.

The Apoptotic Effect of the Hexane Extract of Rheum undulatum L. in Oral Cancer Cells through the Down-regulation of Specificity Protein 1 and Survivin

Lab Anim Res. 2011 Mar;27(1):19-24.
Figure 5

The effect of hexane extract of Rheum undulatum L. (HERL) on the regulation of Sp1 and survivin protein expression. Sp1 and survivin protein levels were analyzed by Western blot analysis.

The Apoptotic Effect of the Hexane Extract of Rheum undulatum L. in Oral Cancer Cells through the Down-regulation of Specificity Protein 1 and Survivin

Lab Anim Res. 2011 Mar;27(1):19-24.
Figure 2

The effect of hexane extract of Rheum undulatum L. (HERL) on cell accumulation in sub-G₁ phase. The sub-G₁ population was measured by PI staining and flow cytometry analysis. The bar graph represents three independent experiments and mean±SD. ^*P<0.05 compared to control group.

The Apoptotic Effect of the Hexane Extract of Rheum undulatum L. in Oral Cancer Cells through the Down-regulation of Specificity Protein 1 and Survivin

Lab Anim Res. 2011 Mar;27(1):19-24.